Publikationen 2006

Accardi, A. Lobet, S. Williams, C. Miller, C. & Dutzler, R. Synergism between halide binding and proton transport in a CLC-type exchanger. J. Mol. Biol. 362, 691-699 (2006).

Amstutz, P., Binz, H. K., Zahnd, C. & Plückthun, A. in Cell Biology - A Laboratory Handbook (ed. Celis, J.) 497–509 (Elsevier Academic Press, 2006).

Amstutz, P., Koch, H., Binz, H. K., Deuber, S. A. & Plückthun, A. Rapid selection of specific MAP kinase-binders from designed ankyrin repeat protein libraries. Protein Eng. Des. Sel. 19, 219–229 (2006).

Baici, A. Enzyme kinetics: the velocity of reactions. The Biochemist 28, 36–39 (2006).

Baici, A., Müntener, K., Willimann, A. & Zwicky, R. Regulation of human cathepsin B by alternative  m RNA splicing: homeostasis, fatal errors and cell death. Biol. Chem. 387, 1017-1021 (2006).  

Bès, C. T., S. Chentouf, M. Breton, H. Lajoix, A. D. Heitz, F. Gross, R. Plückthun, A. & Chardès, T. PIN-bodies: a new class of antibody-like proteins with CD4 specificity derived from the protein inhibitor of neuronal nitric oxide synthase. Biochem. Biophys. Res. Commun. 343, 334–44 (2006).

Binz, H., Kohl, A., Plückthun, A. & Grütter, M. Crystal structure of a consensus-designed ankyrin repeat protein: Implications for stability. Proteins (2006).

Bjelic, S., Karshikoff, A. & Jelesarov, I. Stability and folding/unfolding kinetics of the homotrimeric coiled coil Lpp-56. Biochemistry 45, 8931-8939 (2006).

Caflisch, A. Computational models for the prediction of polypeptide aggregation propensity. Curr. Opin. Chemic. Biol. 10, 437-444 (2006).

Caflisch, A. Network and graph analyses of folding free energy surfaces. Curr. Opin. Struct. Biol. 16, 71–78 (2006).

Camenisch, U., Dip, R., Schumacher, S. B., Schuler, B. & Naegeli, H. Recognition of helical kinks by xeroderma pigmentosum group A protein triggers DNA excision repair. Nat. Struct. Mol. Biol. 13, 278–284 (2006).

Capitani G., Eidam O., Glockshuber R. & Grütter M.G. Structural and functional insights into the assembly of type 1 pili from Escherichia coli. Microbes Infect. 8, 2284-2290 (2006).

Capitani, G., Eidam, O. & Grütter, M.G. Evidence for a novel domain of bacterial outer membrane ushers. Proteins 65, 816-823 (2006).


Cecchini, M., Curcio, R., Pappalardo, M., Melki, R. & Caflisch, A. A molecular dynamics approach to the structural characterization of amyloid aggregation. J. Mol. Biol. 357, 1306–1321 (2006).

Deller, S., Sollner, S., Trenker-El-Toukhy, R., Jelesarov, I., Gubitz, G. M., Macheroux, P. Characterization of a thermostable NADPH:FMN oxidoreductase from the mesophilic bacterium Bacillus subtilis. Biochemistry 45, 7083-7091(2006).

Devi, V. S., Sprecher, C. B., Hunziker, P., Mittl, P. R. E., Bosshard, H. R. & Jelesarov, I. Disulfide formation and stability of a cysteine-rich repeat protein from Helicobacter pylori. Biochemistry 45, 1599–1607 (2006).

Dutzler R. The ClC family of chloride channels and transporters. Curr. Opin. Struct. Biol. 16, 439-446 (2006).

Ekici O.D., Li Z.Z., Campbell A.J., James K.E., Asgian J.L., Mikolajczyk J., Salvesen G.S., Ganesan R., Jelakovic S., Grütter M.G. & Powers J.C. Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10. J. Med. Chem. 49, 5728-5749 (2006).

Fasan, R., Dias, RL., Moehle, K., Zerbe, O., Obrecht, D., Mittl, P. R. E., Grütter, M. G. & Robinson, J.A. Structure-activity studies in a family of beta-hairpin protein epitope mimetic inhibitors of the p53-HDM2 protein-protein interaction. Chembiochem 7, 515–526 (2006).

Frey, D., Braun, O., Briand, C., Vasak, M. & Grütter, M. G. Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors. Structure 14, 901–911 (2006).

Galliciotti, G. & Sonderegger, P. Neuroserpin. Frontiers in Bioscience 11, 33–45 (2006).

Ganesan R., Jelakovic S., Campbell A.J., Li Z.Z., Asgian J.L., Powers J.C. & Grütter M.G. Exploring the S4 and S1 prime subsite specificities in caspase-3 with aza-peptide epoxide inhibitors. Biochemistry 45, 9059-9067 (2006).

Ganesan R., Mittl P.R., Jelakovic S. & Grütter M.G. Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis. J Mol Biol. 359, 1378-1388 (2006).